By Jos Kleinjans
Toxicogenomics-Based mobile Models is a distinct and priceless reference for all educational researchers using toxicogenomic tools with appreciate to animal trying out for chemical defense. This source deals state-of-the-art details at the software of toxicogenomics to constructing possible choices to present animal toxicity checks. via illustrating the advance of toxicogenomics-based mobile types for serious endpoints of toxicity and supplying real-world examples for validation and information research, this e-book presents an review of the present country of the sector, in addition to possibilities and demanding situations for the longer term. Written by way of well known foreign toxicological specialists, this e-book explores ‘omics know-how for constructing new assays for toxicity trying out and security evaluate and offers the reader with a centred exam of other potential to animal testing.
- Describes the cutting-edge in constructing toxicogenomics-based mobile types for chemical-induced carcinogenicity, immunotoxicity, developmental toxicity, neurotoxicity and copy toxicity
- Illustrates tips on how to validate toxicogenomics-based replacement try types and offers an outlook to societal and monetary implementation of those novel assays
- Includes an outline of present trying out tools and danger review frameworks
- Provides a real-world evaluate via articulating the present improvement and demanding situations in toxicogenomics whereas suggesting how you can flow this box forward